KMID : 0356620020170050713
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Journal of Korean Society of Endocrinology 2002 Volume.17 No. 5 p.713 ~ p.719
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A Case of Lymphocytic Hypophysitis in a Postmenopausal Woman
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Baik Sang-Hyun
Kim Dong-Sun Sung Yoon-Kyoung Kim Jong-Pyo Lee Chang-Beom Park Yong-Soo Choi Woong-Hwan Ahn You-Hern Kim Tae-Wha Ko Yong Park Moon-Hyang
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Abstract
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A 64-year-old Korean woman presented with a 3-week history of severe headache and ocular pain. Her brain MRI showed a cystic pituitary mass compressing the optic chiasm. A hormonal study revealed anterior pituitary insufficiency and a slightly increased prolactin level. We performed a transsphenoidal resection of the pituitary mass. A pathological examination revealed the presence of a heavy inflammatory infiltrate, composed of lymphocytes and plasma cells, and destruction of the adenohypophysial structures. Five months after surgery, her hormonal levels had nearly normalized, without hormone replacement therapy. A follow-up MRI showed no recurrence. We conclude that lymphocytic hypophysitis should be included in the differential diagnosis of pituitary mass at any age. We discuss the features that can help to make a preoperative differential diagnosis, and selection of the appropriate treatment.
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KEYWORD
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Lymphocytic hypophysitis, Pituitary, Postmenopausal woman
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